Prof. Dr. Rumen Krastev

Biophysikalische Chemie, Oberflächen

+49 7121 271 2062

rumen.krastev@reutlingen-university.de

Gebäude 2, Raum 116

Während der Vorlesungszeit:

Mittwoch 10.00 bis 12.00 Uhr und nach Vereinbarung

Leiter Gruppe "Intelligente Oberflächen"
Stellvertretender Leiter Gruppe "Biofunktionalisierte Oberflächen" am NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen

Vorlesungen:

Biophysikalische Chemie
Oberflächen

Praktika:

Biophysikalische Chemie

Kompatibilität zwischen Materialien und Geweben
Oberflächenmodifizierungen
Drug Releasing Implantate
Schäume und Anti-Schäume

MediFrei Stent - Medikamentenfreie kontaktwirkende immunsuppressive Beschichtungen für vaskuläre Stents. Ein Projekt im Rahmen des Programms “Innovative Projekte / Kooperationsprojekte” an den Hochschulen Baden-Württemberg
InSeL - Innovative Schaumstrukturen für effizienten Leichtbau. Ein Projekt im Rahmen des Operationellen Programms für Stärkung von Forschung, technologischer Entwicklung und Innovation an staatlichen Hochschulen in Baden-Württemberg (ZAFH)

Krastev, Rumen

2024
Andreeva, Tonya; Walker, Oliver; Rudt, Alexander; Jung, Ole; Barbeck, Mike; Gülcher, Manfred; Krastev, Rumen (2024): Composite polymer/wax coatings as a corrosion barrier of bioresorbable magnesium coronary stents. - In: Heliyon 10 (13). - S. 1-13. - DOI: https://doi.org/10.1016/j.heliyon.2024.e34025	BibTeX \| RIS DOI URN
Andreeva, Tonya; Rudt, Alexander; László, Fábián; Ayaydin, Ferhan; Iliev, Ivan; Jung, Ole; Barbeck, Mike; Dér, Andras; Krastev, Rumen; Taneva, Stefka (2024): Control of cell adhesion and growth on polysaccharide-based multilayer coatings by incorporation of graphene oxide. - In: Coatings 14 (5). - S. 1-14. - DOI: https://doi.org/10.3390/coatings14050570	BibTeX \| RIS DOI URN
2023
Liu, Yuangang; Krastev, Rumen; Wei, Junchao; Jiang, Min (2023): Functional surfaces and biomaterials. - In: Frontiers in Bioengineering and Biotechnology 11 (Artikelnummer: 1138172) - S. 1-2. - DOI: https://doi.org/10.3389/fbioe.2023.1138172	BibTeX \| RIS DOI URN
Andreeva, Tonya; Drieschner, Tobias; Golovko, Dmytro; Lorenz, Anita; Rebner, Karsten; Krastev, Rumen (2023): Process validation and a new method for quality control of ultrathin polyelectrolyte multilayer coatings. - In: Colloids and surfaces : an international journal devoted to the principles and applications of colloid and interface science. A, Physicochemical and engineering aspects 676 (Artikelnummer: 132157) - DOI: https://doi.org/10.1016/j.colsurfa.2023.132157	BibTeX \| RIS DOI
Ren, Yanru; Liu, Luo; Xiong, Xin; Krastev, Rumen; Smeets, Ralf; Rimashevskiy, Denis; Schnettler, Reinhard; Alkildani, Said; Emmert, Steffen; Jung, Ole; Barbeck, Mike (2023): Suitability of R. pulmo jellyfish-collagen-coated well plates for cytocompatibility analyses of biomaterials. - In: International journal of molecular sciences 24 (3). - 13 S. - DOI: https://doi.org/10.3390/ijms24033007	BibTeX \| RIS DOI URN
2021
Billing, Florian; Walter, Bernadette; Fink, Simon; Arefaine, Elsa; Pickarski, Luisa; Maier, Sandra; Kretz, Robin; Jakobi, Meike; Feuerer, Nora; Schneiderhan-Marra, Nicole; Burkhardt, Claus; Templin, Markus; Zeck, Anne; Krastev, Rumen; Hartmann, Hanna; Shipp, Christopher (2021): Altered proinflammatory responses to polyelectrolyte multilayer coatings are associated with differences in protein adsorption and wettability. - In: ACS applied materials & interfaces 13 (46). - S. 55534-55549. - DOI: https://doi.org/10.1021/acsami.1c16175	BibTeX \| RIS DOI URN
Wang, Pei; Kankala, Ranjith; Chen, Biaoqi; Zhang, Yang; Zhu, Mingzhi; Li, Xuemei; Long, Ruimin; Yang, Dayun; Krastev, Rumen; Wang, Shibin; Xiong, Xin; Liu, Yuangang (2021): Cancer cytomembrane-cloaked Prussian blue nanoparticles enhance the efficacy of mild-temperature photothermal therapy by disrupting mitochondrial functions of cancer cells. - In: ACS applied materials & interfaces 13 (31). - S. 37563-37577. - DOI: https://doi.org/10.1021/acsami.1c11138	BibTeX \| RIS DOI
Rudt, Alexander; Sun, Jing; Qin, Meng; Liu, Luo; Syldatk, Christoph; Barbeck, Mike; Xiong, Xin; Krastev, Rumen (2021): Controlled adhesion of HUVEC on polyelectrolyte multilayers by regulation of coating conditions. - In: ACS applied bio materials 4 (2). - S. 1441-1449. - DOI: https://doi.org/10.1021/acsabm.0c01330	BibTeX \| RIS DOI
Shahriari-Khalaji, Mina; Hu, Gaoquan; Chen, Lin; Cao, Zhangjun; Andreeva, Tonya; Xiong, Xin; Krastev, Rumen; Hong, Feng (2021): Functionalization of aminoalkylsilane-grafted bacterial nanocellulose with ZnO-NPs-doped pullulan electrospun nanofibers for multifunctional wound dressing. - In: ACS biomaterials science & engineering 7 (8). - S. 3933-3946. - DOI: https://doi.org/10.1021/acsbiomaterials.1c00444	BibTeX \| RIS DOI
Jung, Ole; Barbeck, Mike; Fan, Lu; Korte, Fabian; Zhao, Cuifeng; Krastev, Rumen; Pantermehl, Sven; Xiong, Xin (2021): In vitro and ex vivo analysis of collagen foams for soft and hard tissue regeneration. - In: In vivo : international journal of experimental and clinical pathophysiology and drug research 35 (5). - S. 2541-2549. - DOI: https://doi.org/10.21873/invivo.12536	BibTeX \| RIS DOI URN
Ullah, Sadeeq; Khan, Shahin; Ren, Yanru; Zhang, Xu; Qin, Meng; Xiong, Xin; Krastev, Rumen; Jan, Amin; Liu, Luo; Yuan, Qipeng (2021): Near-infrared laser 808-nm excitable palladium nano-dots loaded on graphene oxide hybrid for the antibacterial activity. - In: Applied organometallic chemistry 35 (11). - 11 S. - DOI: https://doi.org/10.1002/aoc.6380	BibTeX \| RIS DOI
Liu, Xiudong; Zhou, Huofei; Yu, Weiting; Xiong, Xu; Krastev, Rumen; Ma, Xiaojun (2021): Preparation of cationic amphiphilic nanoparticles with modified chitosan derivatives for doxorubicin delivery. - In: Materials 14 (22). - 11 S. - DOI: https://doi.org/10.3390/ma14227010	BibTeX \| RIS DOI URN
Kapogianni, Eleni; Alkildani, Said; Radenkovic, Milena; Xiong, Xin; Krastev, Rumen; Stöwe, Ignacio; Bielenstein, James; Jung, Ole; Najman, Stevo; Barbeck, Mike; Rothamel, Daniel (2021): The early fragmentation of a bovine dermis-derived collagen barrier membrane contributes to transmembraneous vascularization : a possible paradigm shift for Guided Bone Regeneration. - In: Membranes 11 (3). - 16 S. - DOI: https://doi.org/10.3390/membranes11030185	BibTeX \| RIS DOI URN
Abels, Manuel; Alkildani, Said; Pröhl, Annica; Xiong, Xin; Krastev, Rumen; Korzinskas, Tadas; Stojanovic, Sanja; Jung, Ole; Najman, Stevo; Barbeck, Mike (2021): The granule size mediates the in vivo foreign body response and the integration behavior of bone substitutes. - In: Materials 14 (23). - 15 S. - DOI: https://doi.org/10.3390/ma14237372	BibTeX \| RIS DOI URN
2020
Rudt, Alexander; Andreeva, Tonya; Krastev, Rumen; Taneva, Stefka (2020): Composite polyelectrolyte multilayers for biofunctionalization of medical devices. - In: Current directions in biomedical engineering 6 (3). - S. 1-4. - DOI: https://doi.org/10.1515/cdbme-2020-3110	BibTeX \| RIS DOI URN
Barbeck, Mike; Kühnel, Lennart; Witte, Frank; Pissarek, Jens; Precht, Clarissa; Xiong, Xin; Krastev, Rumen; Wegner, Nils; Walther, Frank; Jung, Ole (2020): Degradation, bone regeneration and tissue response of an innovative volume stable magnesium-supported GBR/GTR barrier membrane. - In: International journal of molecular sciences 21 (9). - S. 1-22. - DOI: https://doi.org/10.3390/ijms21093098	BibTeX \| RIS DOI URN
Iyota, Hidemi; Krastev, Rumen (2020): Equilibrium thickness of foam films and adsorption of ions at surfaces: Water and aqueous solutions of sodium chloride, hydrochloric acid, and sodium hydroxide. - In: Journal of colloid and interface science : JCIS 565 - S. 405-415. - DOI: https://doi.org/10.1016/j.jcis.2019.12.042	BibTeX \| RIS DOI
Djanklich, Leyla; Andreeva, Tonya; Xiong, Xin; Krastev, Rumen; Kemkemer, Ralf (2020): Evaluation of antibacterial properties of polyelectrolyte multilayer coatings by norm tests. - In: Current directions in biomedical engineering 6 (3). - S. 1-4. - DOI: https://doi.org/10.1515/cdbme-2020-3122	BibTeX \| RIS DOI URN
Gao, Miaomiao; Guo, Jia; Cao, Hui; Wang, Huqun; Xiong, Xin; Krastev, Rumen; Nie, Kaili; Xu, Haijun; Liu, Luo (2020): Immobilized bacteria with pH-response hydrogel for self-healing of concrete. - In: Journal of environmental management 261 (Artikelnummer: 110225) - S. 1-6. - DOI: https://doi.org/10.1016/j.jenvman.2020.110225	BibTeX \| RIS DOI
Ren, Yanru; Cao, Hui; Xu, Haijun; Xiong, Xin; Krastev, Rumen; Liu, Luo (2020): Improved aging properties of bio-bitumen coating sheets by using modified lignin. - In: Journal of environmental management 274 (Artikelnummer: 111178) - S. 1-5. - DOI: https://doi.org/10.1016/j.jenvman.2020.111178	BibTeX \| RIS DOI
Andreeva, Tonya; Dér, András; Kelemen, Lóránd; Krastev, Rumen; Taneva, Stefka (2020): Modulation of the internal structure and surface properties of natural and synthetic polymer matrices by graphene oxide doping. - In: Polymers for advanced technologies 31 (7). - S. 1562-1570. - DOI: https://doi.org/10.1002/pat.4885	BibTeX \| RIS DOI
2019
Barbeck, Mike; Jung, Ole; Xiong, Xin; Krastev, Rumen; Korzinskas, Tadas; Najman, Stevo (2019): Balancing purification and ultrastructure of naturally derived bone blocks for bone regeneration: report of the purification effort of two bone blocks. - In: Materials / Molecular Diversity Preservation International 12 (19). - S. 1-13. - DOI: https://doi.org/10.3390/ma12193234	BibTeX \| RIS DOI URN
Kapogianni, Eleni; Barbeck, Mike; Jung, Ole; Arslan, Aylin; Kuhnel, Lennart; Xiong, Xin; Krastev, Rumen (2019): Comparison of material-mediated bone regeneration capacities of sintered and non-sintered xenogeneic bone substitutes via 2D and 3D data. - In: In vivo : international journal of experimental and clinical pathophysiology and drug research 33 (6). - S. 2169-2179. - DOI: https://doi.org/10.21873/invivo.11719	BibTeX \| RIS DOI URN
Seidenstuecker, Michael; Lange, Svenja; Esslinger, Steffen; Latorre, Sergio; Krastev, Rumen; Gadow, Rainer (2019): Inversely 3D-printed β-TCP scaffolds for bone replacement. - In: Materials 12 (20). - S. 1-17. - DOI: https://doi.org/10.3390/ma12203417	BibTeX \| RIS DOI URN
2018
Frey, Kerstin; Fischer, Alena; Krastev, Rumen; Kemkemer, Ralf (2018): CurvChip - chip platform for investigating cell responses to curved surface features. - In: Current directions in biomedical engineering 4 (1). - S. 453-456. - DOI: https://doi.org/10.1515/cdbme-2018-0108	BibTeX \| RIS DOI URN
Früh, Johannes; Rühm, Adrian; He, Qiang; Möhwald, Helmuth; Krastev, Rumen; Köhler, Ralf (2018): Elastic to plastic deformation in uniaxially stressed polylelectrolyte multilayer films. - In: Langmuir / American Chemical Society : the ACS journal of surfaces and colloids 34 (40). - S. 11933-11942. - DOI: https://doi.org/10.1021/acs.langmuir.8b01296	BibTeX \| RIS DOI
Krastev, Rumen; Rudt, Alexander; Xiong, Xin; Hartmann, Hanna (2018): Polyelectrolyte coatings for surface modification of medical implants. - In: Current directions in biomedical engineering 4 (1). - S. 213-216. - DOI: https://doi.org/10.1515/cdbme-2018-0053	BibTeX \| RIS DOI URN
2017
Sun, Lili; Xiong, Xin; Zou, Qiaogen; Ouyang, Pingkai; Burkhardt, Claus; Krastev, Rumen (2017): Design of intelligent chitosan/heparin hollow microcapsules for drug delivery. - In: Journal of applied polymer science 134 (5). - S. 1-10. - DOI: https://doi.org/10.1002/app.44425	BibTeX \| RIS DOI
Paradiso, Patrizia; Colaço, Rogério; Mata, José; Krastev, Rumen; Saramago, Benilde; Serro, Ana (2017): Drug release from liposome coated hydrogels for soft contact lenses: the blinking and temperature effect. - In: Journal of biomedical materials research. - Part B. Applied biomaterials 105 (7). - S. 1799-1807. - DOI: https://doi.org/10.1002/jbm.b.33715	BibTeX \| RIS DOI
2016
Guțoaia, Andra; Schuster, Liane; Margutti, Simona; Laufer, Stefan; Schlosshauer, Burkhard; Krastev, Rumen; Stoll, Dieter; Hartmann, Hanna (2016): Fine-tuned PEGylation of chitosan to maintain optimal siRNA-nanoplex bioactivity. - In: Carbohydrate polymers 143 - S. 25-34. - DOI: https://doi.org/10.1016/j.carbpol.2016.01.010	BibTeX \| RIS DOI
Andreeva, Tonya; Danailova, Avgustina; Terziyska, Penka; Krumova, Shashka; Taneva, Stefka; Krastev, Rumen (2016): Hofmeister anions effect on the thickness and morphology of polyelectrolyte multilayers for biofunctionalization of cardiovascular stents. - In: Bulgarian chemical communications 48 (Special issue A). - S. 23-28. - URL: http://www.bcc.bas.bg/	BibTeX \| RIS URN
Gittel, Bianca; Kemkemer, Ralf; Krastev, Rumen; Athanasopulu, Kiriaki; Rudt, Alexander (2016): Modification of polyelectrolyte multilayer coatings using nanoparticles to optimize adhesion and proliferation of different cell types. - In: Bionanomaterials : journal of functional materials, biomechanics, and tissue engineering 17 (S1). - S. 123. - DOI: https://doi.org/10.1515/bnm-2016-1001	BibTeX \| RIS DOI URN
Andreeva, Tonya; Hartmann, Hanna; Taneva, Stefka; Krastev, Rumen (2016): Regulation of the growth, morphology, mechanical properties and biocompatibility of natural polysaccharide-based multilayers by Hofmeister anions. - In: Journal of materials chemistry. - B. Materials for biology and medicine 4 (44). - S. 7092-7100. - DOI: https://doi.org/10.1039/C6TB01638C	BibTeX \| RIS DOI
2015
Eftekhari, Ali Akbar; Krastev, Rumen; Farajzadeh, Rouhi (2015): Foam stabilized by fly ash nanoparticles for enhancing oil recovery. - In: Industrial & engineering chemistry research 54 (50). - S. 12482-12491. - DOI: https://doi.org/10.1021/acs.iecr.5b03955	BibTeX \| RIS DOI
Früh, Johannes; Rühm, Adrian; Möhwald, Helmuth; Krastev, Rumen; Köhler, Ralf (2015): Reflectometry on curved interfaces. - In: Physica / B : Condensed matter 457 - S. 202-211. - DOI: https://doi.org/10.1016/j.physb.2014.08.030	BibTeX \| RIS DOI
2014
Toca-Herrera, José Luis; Krasteva, Nadejda; Müller, Hans-Joachim; Krastev, Rumen (2014): Interactions in lipid stabilised foam films. - In: Advances in colloid and interface science 107 - S. 93-106. - DOI: https://doi.org/10.1016/j.cis.2014.02.016	BibTeX \| RIS DOI
Steuer, Heiko; Krastev, Rumen; Lembert, Nicolas (2014): Metallic oxide nanoparticles stimulate blood coagulation independent of their surface charge. - In: Journal of biomedical materials research : Part B, Applied biomaterials 102 (5). - S. 897-902. - DOI: https://doi.org/10.1002/jbm.b.33051	BibTeX \| RIS DOI
Xiong, Xin; Hossfeld, Susanne; Margutti, Simona; Krastev, Rumen (2014): Polyelectrolyte multilayers as functional coatings for controlled biomolecular interactions. - In: Scholz, Martin (Hrsg.): Biofunctional surface engineering. - Singapore : Pan Stanford Publishing. - S. 47-69. - ISBN: 978-981-4411-61-5.	BibTeX \| RIS
Georgiev, Georgi; Yokoi, Norihiko; Ivanova, Slavyana; Tonchev, Vesselin; Nencheva, Yana; Krastev, Rumen (2014): Surface relaxations as a tool to distinguish the dynamic interfacial properties of films formed by normal and diseased meibomian lipids. - In: Soft matter 10 (30). - S. 5579-5588. - DOI: https://doi.org/10.1039/C4SM00758A	BibTeX \| RIS DOI