Prof. Dr. Petra Kluger

Leitung Kluger-Lab

+49 7121 271 2061

petra.kluger@reutlingen-university.de

Gebäude 2, Raum 118

Während der Vorlesungszeit:

nach Vereinbarung

Humanbiologie
Praktikum Chemische Grundlagen der Biomedizin
Wissenschaftliches Arbeiten und Grundlagen der Biomedizin
Tissue Engineering
Immunologie
Biofabrication & Regenerative Medicine

Tissue Engineering
Zellmaterial-Interaktionen
Biomaterialien, Oberflächenmodifikation
Zellbasierte in-vitro Testsysteme

Berufliche Stationen

01/2019 - 12/2028	Assoziation an der Fakultät für Naturwissenschaften der Universität Hohenheim, Deutschland, mit dem Recht zur Verleihung des Doktorgrades (Dr. rer. nat.)
Since 09/2018	Vizepräsidentin für Forschung der Hochschule Reutlingen, Deutschland
Since 11/2017	Professorin (W3) für Tissue Engineering und Biofabrikation an der Hochschule Reutlingen, Deutschland
11/2013 – 10/2017	Shared-Professor (W3) für Tissue Engineering (49%) an der Hochschule Reutlingen, Deutschland
05/2013 – 10/2017	Leitung der Abteilung Zell- und Gewebetechnik (51%) am Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik (IGB) in Stuttgart, Deutschland
05/2009 – 04/2012	Stellvertretende Leitung der Abteilung Zell- und Tissue Engineering und Gruppenleitung am Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik (IGB) in Stuttgart, Deutschland

Aus- und Weiterbildung

08/2016 – 09/2016	DAAD-Kurzzeitdozentur (Stipendium) für die Lehre der Biofabrikation am Worcester Polytechnic Institute in Massachusetts, USA)
10/2010 – 10/2011	Baden-Württembergisches Zertifikat für Hochschuldidaktik 150 h Fortbildung in verschiedenen Bereichen der Didaktik
07/2009	Promotionsprüfung an der Universität Stuttgart, Deutschland (summa cum laude)
05/2006 – 04/2009	Promotionsstipendium der Peter und Traudl Engelhorn Stiftung
11/2007 – 11/2008	Postgraduales Fernstudium der Nanobiotechnologie an der Universität Kaiserslautern; Abschlussnote: "gut"
10/2000 – 04/2006	Studium der Technischen Biologie an der Universität Stuttgart, Abschlussnote: "ausgezeichnet".

Sonstige Funktionen

Intern

Prüfungsausschuss Bachelor Biomedizinische Wissenschaften
Prüfungsausschuss Master Biomedical Sciences
Mitglied der Studienkommission

Extern

Stellvertretende Vorsitzende der Deutschen Gesellschaft für Biomaterialien
Vorstandsmitglied der BioMedTech e.V.
Mitglied im Kuratorium des Naturwissenschaftlichen und Medizinischen Instituts an der Universität Tübingen

Kluger, Petra

2024
Albrecht, Franziska; Ahlfeld, Tilman; Klatt, Annemarie; Heine, Simon; Gelinsky, Michael; Kluger, Petra (2024): Biofabrication's contribution to the evolution of cultured meat. - In: Advanced healthcare materials 13 (13). - S. 1-21. - DOI: https://doi.org/10.1002/adhm.202304058	BibTeX \| RIS DOI URN
Heine, Simon; Ahlfeld, Tilman; Albrecht, Franziska; Gelinsky, Michael; Kluger, Petra (2024): How biofabrication can accelerate cultured meat’s path to market. - In: Nature reviews. Materials 9 (2). - S. 83-85. - DOI: https://doi.org/10.1038/s41578-024-00650-9	BibTeX \| RIS DOI
Albrecht, Franziska; Schmidt, Freia; Schmidt, Christian; Börret, Rainer; Kluger, Petra (2024): Robot-based 6D bioprinting for soft tissue biomedical applications. - In: Engineering in life sciences 24 (7). - S. 1-11. - DOI: https://doi.org/10.1002/elsc.202300226	BibTeX \| RIS DOI URN
2023
Nellinger, Svenja; Kluger, Petra (2023): How mechanical and physicochemical material characteristics influence adipose-derived stem cell fate. - In: International journal of molecular sciences 24 (4). - S. 1-26. - DOI: https://doi.org/10.3390/ijms24043551	BibTeX \| RIS DOI URN
2022
Nellinger, Svenja; Rapp, Mareike; Southan, Alexander; Wittmann, Valentin; Kluger, Petra (2022): An advanced ‘clickECM’ that can be modified by the inverse-electron demand Diels-Alder reaction. - In: ChemBioChem 23 (1). - S. 1-9. - DOI: https://doi.org/10.1002/cbic.202100266	BibTeX \| RIS DOI URN
Albrecht, Franziska; Schmidt, Freia; Volz, Ann-Cathrin; Kluger, Petra (2022): Bioprinting of 3D adipose tissue models using a GelMA-bioink with human mature adipocytes or human adipose-derived stem cells. - In: Gels 8 (10). - 19 S. - DOI: https://doi.org/10.3390/gels8100611	BibTeX \| RIS DOI URN
Nellinger, Svenja; Mrsic, Ivana; Keller, Silke; Heine, Simon; Southan, Alexander; Bach, Monika; Volz, Ann-Cathrin; Chassé, Thomas; Kluger, Petra (2022): Cell-derived and enzyme-based decellularized extracellular matrix exhibit compositional and structural differences that are relevant for its use as a biomaterial. - In: Biotechnology and bioengineering 119 (4). - S. 1142-1156. - DOI: https://doi.org/10.1002/bit.28047	BibTeX \| RIS DOI URN
Albrecht, Franziska; Dolderer, Vera; Nellinger, Svenja; Schmidt, Freia; Kluger, Petra (2022): Gellan gum is a suitable biomaterial for manual and bioprinted setup of long-term stable, functional 3D-adipose tissue models. - In: Gels 8 (7). - 17 S. - DOI: https://doi.org/10.3390/gels8070420	BibTeX \| RIS DOI URN
Wollschlaeger, Jannis; Maatz, Robin; Albrecht, Franziska; Klatt, Annemarie; Heine, Simon; Blaeser, Andreas; Kluger, Petra (2022): Scaffolds for cultured meat on the basis of polysaccharide hydrogels enriched with plant-based proteins. - In: Gels 8 (2). - 21 S. - DOI: https://doi.org/10.3390/gels8020094	BibTeX \| RIS DOI URN
2021
Keller, Silke; Bakker, Tomke; Kimmel, Benjamin; Rebers, Lisa; Götz, Tobias; Tovar, Günter; Kluger, Petra; Southan, Alexander (2021): Azido‐functionalized gelatin via direct conversion of lysine amino groups by diazo transfer as a building block for biofunctional hydrogels. - In: Journal of biomedical materials research, Part A 109 (1). - S. 77-91. - DOI: https://doi.org/10.1002/jbm.a.37008	BibTeX \| RIS DOI URN
Dani, Sophie; Ahlfeld, Tilman; Albrecht, Franziska; Duin, Sarah; Kluger, Petra; Lode, Anja; Gelinsky, Michael (2021): Homogeneous and reproducible mixing of highly viscous biomaterial inks and cell suspensions to create bioinks. - In: Gels 7 (4). - 17 S. - DOI: https://doi.org/10.3390/gels7040227	BibTeX \| RIS DOI URN
2020
Nellinger, Svenja; Schmidt, Isabelle; Heine, Simon; Volz, Ann-Cathrin; Kluger, Petra (2020): Adipose stem cell-derived extracellular matrix represents a promising biomaterial by inducing spontaneous formation of prevascular-like structures by mvECs. - In: Biotechnology & Bioengineering 117 (10). - S. 3160-3172. - DOI: https://doi.org/10.1002/bit.27481	BibTeX \| RIS DOI URN
Leucht, Annika; Volz, Ann-Cathrin; Rogal, Julia; Borchers, Kirsten; Kluger, Petra (2020): Advanced gelatin-based vascularization bioinks for extrusion-based bioprinting of vascularized bone equivalents. - In: Scientific reports 10 (Artikelnummer: 5330) - S. 1-15. - DOI: https://doi.org/10.1038/s41598-020-62166-w	BibTeX \| RIS DOI URN
Keller, Silke; Wörgötter, Katharina; Liedek, Anke; Kluger, Petra; Bach, Monika; Tovar, Günter; Southan, Alexander (2020): Azide-functional extracellular matrix coatings as a bioactive platform for bioconjugation. - In: ACS applied materials & interfaces 12 (24). - S. 26868-26879. - DOI: https://doi.org/10.1021/acsami.0c04579	BibTeX \| RIS DOI
Kluger, Petra; Nellinger, Svenja; Heine, Simon; Volz, Ann-Cathrin (2020): Cell-derived extracellular matrix as maintaining biomaterial for adipogenic differentiation. - In: Current Directions in Biomedical Engineering 6 (3). - S. 1-4. - DOI: https://doi.org/10.1515/cdbme-2020-3106	BibTeX \| RIS DOI URN
Keller, Silke; Liedek, Anke; Shendi, Dalia; Bach, Monika; Tovar, Günter; Kluger, Petra; Southan, Alexander (2020): Eclectic characterisation of chemically modified cell-derived matrices obtained by metabolic glycoengineering and re-assessment of commonly used methods. - In: RSC Advances 10 (58). - S. 35273-35286. - DOI: https://doi.org/10.1039/D0RA06819E	BibTeX \| RIS DOI URN
Schmidt, Freia; Nowakowski, Sophia; Kluger, Petra (2020): Improvement of a three-layered in vitro skin model for topical application of irritating substances. - In: Frontiers in Bioengineering and Biotechnology 8 (Artikelnummer: 388) - S. 1-11. - DOI: https://doi.org/10.3389/fbioe.2020.00388	BibTeX \| RIS DOI URN
Kleinhans, Claudia; Schmohl, Lena; Barz, Jakob; Kluger, Petra (2020): Low-pressure plasma activation enables enhanced adipose-derived stem cell adhesion. - In: Journal of biomedical materials research : Part B, Applied biomaterials 108 (4). - S. 1527-1535. - DOI: https://doi.org/10.1002/jbm.b.34500	BibTeX \| RIS DOI
2019
Volz, Ann-Cathrin; Hack, Larissa; Kluger, Petra (2019): A cellulose-based material for vascularized adipose tissue engineering. - In: Journal of biomedical materials research. - Part B, Applied biomaterials 107 (5). - S. 1431-1439. - DOI: https://doi.org/10.1002/jbm.b.34235	BibTeX \| RIS DOI
Huber, Birgit; Hoch, Eva; Calderon, Iván; Borchers, Kirsten; Kluger, Petra (2019): A versatile perfusion bioreactor and endothelializable photo cross-linked tubes of gelatin methacryloyl as promising tools in tissue engineering. - In: Biomedical engineering = Biomedizinische Technik 64 (4). - S. 397-406. - DOI: https://doi.org/10.1515/bmt-2018-0015	BibTeX \| RIS DOI
Volz, Ann-Cathrin; Omengo, Birgit; Gehrke, Sandra; Kluger, Petra (2019): Comparing the use of differentiated adipose-derived stem cells and mature adipocytes to model adipose tissue in vitro. - In: Differentiation : the journal of the International Society of Differentiation 110 (November - December 2019). - S. 19-28. - DOI: https://doi.org/10.1016/j.diff.2019.09.002	BibTeX \| RIS DOI
Nellinger, Svenja; Keller, Silke; Southan, Alexander; Wittmann, Valentin; Volz, Ann-Cathrin; Kluger, Petra (2019): Generation of an azide-modified extracellular matrix by adipose-derived stem cells using metabolic glycoengineering. - In: Current directions in biomedical engineering 5 (1). - S. 393-396. - DOI: https://doi.org/10.1515/cdbme-2019-0099	BibTeX \| RIS DOI URN
Novosel, Esther; Borchers, Kirsten; Kluger, Petra; Mantalaris, Athanasios; Matheis, Georg; Pistolesi, Massimo; Schneider, Jörg; Wenz, Annika (2019): New approaches to respiratory assist: bioengineering an ambulatory, miniaturized bioartificial lung. - In: ASAIO Journal 65 (5). - S. 422-429. - DOI: https://doi.org/10.1097/MAT.0000000000000841	BibTeX \| RIS DOI
2018
Shkarina, Svetlana; Shkarin, Roman; Weinhardt, Venera; Melnik, Elizaveta; Vacun, Gabriele; Kluger, Petra; Loza, Kateryna; Epple, Matthias (2018): 3D biodegradable scaffolds of polycaprolactone with silicate-containing hydroxyapatite microparticles for bone tissue engineering: high-resolution tomography and in vitro study. - In: Scientific reports 8 (Aufsatz 8907). - S. 1-13. - DOI: https://doi.org/10.1038/s41598-018-27097-7	BibTeX \| RIS DOI URN
Volz, Ann-Cathrin; Hack, Larissa; Atzinger, Franziska; Kluger, Petra (2018): Completely defined co-culture of adipogenic differentiated ASCs and microvascular endothelial cells. - In: ALTEX : Alternatives to animal experimentation 35 (4). - S. 464-476. - DOI: https://doi.org/10.14573/altex.1802191	BibTeX \| RIS DOI URN
Volz, Ann-Cathrin; Kluger, Petra (2018): Completely serum-free and chemically defined adipocyte development and maintenance. - In: Cytotherapy 20 (4). - S. 576-588. - DOI: https://doi.org/10.1016/j.jcyt.2018.01.004	BibTeX \| RIS DOI
Wenz, Annika; Tjoeng, Iva; Schneider, Isabelle; Kluger, Petra; Borchers, Kirsten (2018): Improved vasculogenesis and bone matrix formation through coculture of endothelial cells and stem cells in tissue‐specific methacryloyl gelatin‐based hydrogels. - In: Biotechnology & bioengineering 115 (10). - S. 2643-2653. - DOI: https://doi.org/10.1002/bit.26792	BibTeX \| RIS DOI
Schmid, Franziska; Kleinhans, Claudia; Schmid, Freia; Kluger, Petra (2018): Osteoclast formation within a Human co-culture system on bone material as an in vitro model for bone remodeling processes. - In: Journal of functional morphology and kinesiology : JFMK 3 (1). - S. 1-16. - DOI: https://doi.org/10.3390/jfmk3010017	BibTeX \| RIS DOI URN
2017
Wenz, Annika; Borchers, Kirsten; Tovar, Günter; Kluger, Petra (2017): Bone matrix production in hydroxyapatite-modified hydrogels suitable for bone bioprinting. - In: Biofabrication 9 (4). - S. 1-14. - DOI: https://doi.org/10.1088/1758-5090/aa91ec	BibTeX \| RIS DOI
Volz, Ann-Cathrin; Huber, Birgit; Schwandt, Alina Maria; Kluger, Petra (2017): EGF and hydrocortisone as critical factors for the co-culture of adipogenic differentiated ASCs and endothelial cells. - In: Differentiation : the journal of the International Society of Differentiation 95 (May - June 2017). - S. 21-30. - DOI: https://doi.org/10.1016/j.diff.2017.01.002	BibTeX \| RIS DOI
Ruff, Sybil Mara; Keller, Silke; Wieland, Daniel; Wittmann, Valentin; Tovar, Günter; Bach, Monika; Kluger, Petra (2017): clickECM : development of a cell-derived extracellular matrix with azide functionalities. - In: Acta biomaterialia (52)- S. 159-170. - DOI: https://doi.org/10.1016/j.actbio.2016.12.022	BibTeX \| RIS DOI
2016
Volz, Ann-Cathrin; Huber, Birgit; Kluger, Petra (2016): Adipose-derived stem cell differentiation as a basic tool for vascularized adipose tissue engineering. - In: Differentiation : the journal of the International Society of Differentiation 92 (1-2). - S. 52-64. - DOI: https://doi.org/10.1016/j.diff.2016.02.003	BibTeX \| RIS DOI
Huber, Birgit; Engelhardt, Sascha; Meyer, Wolfdietrich; Krüger, Hartmut; Wenz, Annika; Schönhaar, Veronika; Tovar, Günter; Kluger, Petra; Borchers, Kirsten (2016): Blood-vessel mimicking structures by stereolithographic fabrication of small porous tubes using cytocompatible polyacrylate elastomers, biofunctionalization and endothelialization. - In: Journal of functional biomaterials 7 (2). - S. 1-18. - DOI: https://doi.org/10.3390/jfb7020011	BibTeX \| RIS DOI URN
Wenz, Annika; Janke, Katharina; Hoch, Eva; Tovar, Günter; Borchers, Kirsten; Kluger, Petra (2016): Hydroxyapatite-modified gelatin bioinks for bone bioprinting. - In: Bionanomaterials : journal of functional materials, biomechanics, and tissue engineering 17 (3-4). - S. 179-184. - DOI: https://doi.org/10.1515/bnm-2015-0018	BibTeX \| RIS DOI
Huber, Birgit; Czaja, Alina Maria; Kluger, Petra (2016): Influence of epidermal growth factor (EGF) and hydrocortisone on the co-culture of mature adipocytes and endothelial cells for vascularized adipose tissue engineering. - In: Cell biology international 40 (5). - S. 569-578. - DOI: https://doi.org/10.1002/cbin.10595	BibTeX \| RIS DOI
Huber, Birgit; Link, Antonia; Linke, Kirstin; Gehrke, Sandra; Winnefeld, Marc; Kluger, Petra (2016): Integration of mature adipocytes to build up a functional three-layered full-skin equivalent. - In: Tissue engineering / Part C. Methods 22 (8). - S. 756-764. - DOI: https://doi.org/10.1089/ten.tec.2016.0141	BibTeX \| RIS DOI URN
Huber, Birgit; Borchers, Kirsten; Tovar, Günter; Kluger, Petra (2016): Methacrylated gelatin and mature adipocytes are promising components for adipose tissue engineering. - In: Journal of biomaterials applications 30 (6). - S. 699-710. - DOI: https://doi.org/10.1177/0885328215587450	BibTeX \| RIS DOI
2015
Kleinhans, Claudia; Mohan, Ramkumar; Vacun, Gabriele; Schwarz, Thomas; Haller, Barbara; Sun, Yang; Kahlig, Alexander; Kluger, Petra; Finne-Wistrand, Anna; Walles, Heike; Hansmann, Jan (2015): A perfusion bioreactor system efficiently generates cell-loaded bone substitute materials for addressing critical size bone defects. - In: Biotechnology journal 10 (11). - S. 1727-1738. - DOI: https://doi.org/10.1002/biot.201400813	BibTeX \| RIS DOI
Kleinhans, Claudia; Schmid, Freia; Schmid, Franziska; Kluger, Petra (2015): Comparison of osteoclastogenesis and resorption activity of human osteoclasts on tissue culture polystyrene and on natural extracellular bone matrix in 2D and 3D. - In: Journal of biotechnology 205 - S. 101-110. - DOI: https://doi.org/10.1016/j.jbiotec.2014.11.039	BibTeX \| RIS DOI URN
Huber, Birgit; Kluger, Petra (2015): Decelerating mature adipocyte dedifferentiation by media composition. - In: Tissue Engineering / Part C : Methods 21 (12). - S. 1237-1245. - DOI: https://doi.org/10.1089/ten.tec.2015.0166	BibTeX \| RIS DOI
Huber, Birgit; Volz, Ann-Cathrin; Kluger, Petra (2015): How do culture media influence in vitro perivascular cell behavior?. - In: Cell biology international 39 (12). - S. 1395-1407. - DOI: https://doi.org/10.1002/cbin.10515	BibTeX \| RIS DOI
Thude, Sibylle; Kluger, Petra; Schenke-Layland, Katja (2015): In vitro-Hauttestsysteme zur Untersuchung lichtassoziierter Hautschädigung. - In: Biospektrum 21 (2). - S. 172-174. - DOI: https://doi.org/10.1007/s12268-015-0557-z	BibTeX \| RIS DOI
Surmeneva, Maria; Kleinhans, Claudia; Vacun, Gabriele; Kluger, Petra; Schönhaar, Veronika; Müller, Michaela; Hein, Sebastian Boris; Wittmar, Alexandra; Ulbricht, Mathias; Prymak, Oleg; Oehr, Christian; Surmenev, Oleg (2015): Nano-hydroxyapatite-coated metal-ceramic composite ofiron-tricalcium Phosphate : improving the surface wettability,adhesion and proliferation of mesenchymal stem cells in vitro. - In: Colloids and surfaces B : biointerfaces (135)- S. 386-393. - DOI: https://doi.org/10.1016/j.colsurfb.2015.07.057	BibTeX \| RIS DOI
Kleinhans, Claudia; Vacun, Gabriele; Surmenev, Roman; Surmeneva, Maria; Kluger, Petra (2015): Testing the in vitro performance of hydroxyapatite coated magnesium (AZ91D) and titanium concerning cell adhesion and osteogenic differentiation. - In: BioNanoMaterials 16 (1). - S. 41-50. - DOI: https://doi.org/10.1515/bnm-2015-0002	BibTeX \| RIS DOI URN
Huber, Birgit; Volz, Ann-Cathrin; Kluger, Petra (2015): Understanding the effects of mature adipocytes and endothelial cells on fatty acid metabolism and vascular tone in physiological fatty tissue for vascularized adipose tissue engineering. - In: Cell & tissue research 362 (2). - S. 269-279. - DOI: https://doi.org/10.1007/s00441-015-2274-9	BibTeX \| RIS DOI

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