Prof. Dr. Petra Kluger
Head of Kluger-Lab
+49 7121 271 2061
petra.kluger@reutlingen-university.de
Building 2, Room 118
During the lecture period:
by appointment
- Tissue Engineering
- Zellmaterial-Interaktionen
- Biomaterialien, Oberflächenmodifikation
- Zellbasierte in-vitro Testsysteme
Berufliche Stationen
| 01/2019 - 12/2028 | Assoziation an der Fakultät für Naturwissenschaften der Universität Hohenheim, Deutschland, mit dem Recht zur Verleihung des Doktorgrades (Dr. rer. nat.) |
Seit 09/2018 | Vizepräsidentin für Forschung der Hochschule Reutlingen, Deutschland |
Seit 11/2017 | Professorin (W3) für Tissue Engineering und Biofabrikation an der Hochschule Reutlingen, Deutschland |
11/2013 – 10/2017 | Shared-Professor (W3) für Tissue Engineering (49%) an der Hochschule Reutlingen, Deutschland |
05/2013 – 10/2017 | Leitung der Abteilung Zell- und Gewebetechnik (51%) am Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik (IGB) in Stuttgart, Deutschland |
05/2009 – 04/2012 | Stellvertretende Leitung der Abteilung Zell- und Tissue Engineering und Gruppenleitung am Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik (IGB) in Stuttgart, Deutschland |
Aus- und Weiterbildung
08/2016 – 09/2016 | DAAD-Kurzzeitdozentur (Stipendium) für die Lehre der Biofabrikation am Worcester Polytechnic Institute in Massachusetts, USA) |
10/2010 – 10/2011 | Baden-Württembergisches Zertifikat für Hochschuldidaktik 150 h Fortbildung in verschiedenen Bereichen der Didaktik |
07/2009 | Promotionsprüfung an der Universität Stuttgart, Deutschland (summa cum laude) |
05/2006 – 04/2009 | Promotionsstipendium der Peter und Traudl Engelhorn Stiftung |
11/2007 – 11/2008 | Postgraduales Fernstudium der Nanobiotechnologie an der Universität Kaiserslautern; Abschlussnote: "gut" |
10/2000 – 04/2006 | Studium der Technischen Biologie an der Universität Stuttgart, Abschlussnote: "ausgezeichnet". |
Sonstige Funktionen
Intern
- Prüfungsausschuss Bachelor Biomedizinische Wissenschaften
- Prüfungsausschuss Master Biomedical Sciences
- Mitglied der Studienkommission
Extern
- Stellvertretende Vorsitzende der Deutschen Gesellschaft für Biomaterialien
- Vorstandsmitglied der BioMedTech e.V.
- Mitglied im Kuratorium des Naturwissenschaftlichen und Medizinischen Instituts an der Universität Tübingen
Kluger, Petra
2024 | |
| Albrecht, Franziska; Ahlfeld, Tilman; Klatt, Annemarie; Heine, Simon; Gelinsky, Michael; Kluger, Petra (2024): Biofabrication's contribution to the evolution of cultured meat. - In: Advanced healthcare materials 13 (13). - S. 1-21. - DOI: https://doi.org/10.1002/adhm.202304058 | BibTeX | RIS DOIURN |
| Klatt, Annemarie; Wollschlaeger, Jannis; Albrecht, Franziska; Rühle, Sara; Holzwarth, Lena; Hrenn, Holger; Melzer, Tanja; Heine, Simon; Kluger, Petra (2024): Dynamically cultured, differentiated bovine adipose-derived stem cell spheroids as building blocks for biofabricating cultured fat. - In: Nature communications 15 (Artikelnummer: 9107) - S. 1-13. - DOI: https://doi.org/10.1038/s41467-024-53486-w | BibTeX | RIS DOIURN |
| Albrecht, Franziska; Schick, Ann-Kathrin; Klatt, Annemarie; Schmidt, Freia; Nellinger, Svenja; Kluger, Petra (2024): Exploring morphological and molecular properties of different adipose cell models: monolayer, spheroids, gellan gum-based hydrogels, and explants. - In: Macromolecular bioscience (Artikelnummer: 2400320)- S. 1-20. - DOI: https://doi.org/10.1002/mabi.202400320 | BibTeX | RIS DOIURN |
| Heine, Simon; Ahlfeld, Tilman; Albrecht, Franziska; Gelinsky, Michael; Kluger, Petra (2024): How biofabrication can accelerate cultured meat’s path to market. - In: Nature reviews. Materials 9 (2). - S. 83-85. - DOI: https://doi.org/10.1038/s41578-024-00650-9 | BibTeX | RIS DOI |
| Albrecht, Franziska; Schmidt, Freia; Schmidt, Christian; Börret, Rainer; Kluger, Petra (2024): Robot-based 6D bioprinting for soft tissue biomedical applications. - In: Engineering in life sciences 24 (7). - S. 1-11. - DOI: https://doi.org/10.1002/elsc.202300226 | BibTeX | RIS DOIURN |
2023 | |
| Nellinger, Svenja; Kluger, Petra (2023): How mechanical and physicochemical material characteristics influence adipose-derived stem cell fate. - In: International journal of molecular sciences 24 (4). - S. 1-26. - DOI: https://doi.org/10.3390/ijms24043551 | BibTeX | RIS DOIURN |
2022 | |
| Nellinger, Svenja; Rapp, Mareike; Southan, Alexander; Wittmann, Valentin; Kluger, Petra (2022): An advanced ‘clickECM’ that can be modified by the inverse-electron demand Diels-Alder reaction. - In: ChemBioChem 23 (1). - S. 1-9. - DOI: https://doi.org/10.1002/cbic.202100266 | BibTeX | RIS DOIURN |
| Albrecht, Franziska; Schmidt, Freia; Volz, Ann-Cathrin; Kluger, Petra (2022): Bioprinting of 3D adipose tissue models using a GelMA-bioink with human mature adipocytes or human adipose-derived stem cells. - In: Gels 8 (10). - 19 S. - DOI: https://doi.org/10.3390/gels8100611 | BibTeX | RIS DOIURN |
| Nellinger, Svenja; Mrsic, Ivana; Keller, Silke; Heine, Simon; Southan, Alexander; Bach, Monika; Volz, Ann-Cathrin; Chassé, Thomas; Kluger, Petra (2022): Cell-derived and enzyme-based decellularized extracellular matrix exhibit compositional and structural differences that are relevant for its use as a biomaterial. - In: Biotechnology and bioengineering 119 (4). - S. 1142-1156. - DOI: https://doi.org/10.1002/bit.28047 | BibTeX | RIS DOIURN |
| Albrecht, Franziska; Dolderer, Vera; Nellinger, Svenja; Schmidt, Freia; Kluger, Petra (2022): Gellan gum is a suitable biomaterial for manual and bioprinted setup of long-term stable, functional 3D-adipose tissue models. - In: Gels 8 (7). - 17 S. - DOI: https://doi.org/10.3390/gels8070420 | BibTeX | RIS DOIURN |
| Wollschlaeger, Jannis; Maatz, Robin; Albrecht, Franziska; Klatt, Annemarie; Heine, Simon; Blaeser, Andreas; Kluger, Petra (2022): Scaffolds for cultured meat on the basis of polysaccharide hydrogels enriched with plant-based proteins. - In: Gels 8 (2). - 21 S. - DOI: https://doi.org/10.3390/gels8020094 | BibTeX | RIS DOIURN |
2021 | |
| Keller, Silke; Bakker, Tomke; Kimmel, Benjamin; Rebers, Lisa; Götz, Tobias; Tovar, Günter; Kluger, Petra; Southan, Alexander (2021): Azido‐functionalized gelatin via direct conversion of lysine amino groups by diazo transfer as a building block for biofunctional hydrogels. - In: Journal of biomedical materials research, Part A 109 (1). - S. 77-91. - DOI: https://doi.org/10.1002/jbm.a.37008 | BibTeX | RIS DOIURN |
| Dani, Sophie; Ahlfeld, Tilman; Albrecht, Franziska; Duin, Sarah; Kluger, Petra; Lode, Anja; Gelinsky, Michael (2021): Homogeneous and reproducible mixing of highly viscous biomaterial inks and cell suspensions to create bioinks. - In: Gels 7 (4). - 17 S. - DOI: https://doi.org/10.3390/gels7040227 | BibTeX | RIS DOIURN |
2020 | |
| Nellinger, Svenja; Schmidt, Isabelle; Heine, Simon; Volz, Ann-Cathrin; Kluger, Petra (2020): Adipose stem cell-derived extracellular matrix represents a promising biomaterial by inducing spontaneous formation of prevascular-like structures by mvECs. - In: Biotechnology & Bioengineering 117 (10). - S. 3160-3172. - DOI: https://doi.org/10.1002/bit.27481 | BibTeX | RIS DOIURN |
| Leucht, Annika; Volz, Ann-Cathrin; Rogal, Julia; Borchers, Kirsten; Kluger, Petra (2020): Advanced gelatin-based vascularization bioinks for extrusion-based bioprinting of vascularized bone equivalents. - In: Scientific reports 10 (Artikelnummer: 5330) - S. 1-15. - DOI: https://doi.org/10.1038/s41598-020-62166-w | BibTeX | RIS DOIURN |
| Keller, Silke; Wörgötter, Katharina; Liedek, Anke; Kluger, Petra; Bach, Monika; Tovar, Günter; Southan, Alexander (2020): Azide-functional extracellular matrix coatings as a bioactive platform for bioconjugation. - In: ACS applied materials & interfaces 12 (24). - S. 26868-26879. - DOI: https://doi.org/10.1021/acsami.0c04579 | BibTeX | RIS DOI |
| Kluger, Petra; Nellinger, Svenja; Heine, Simon; Volz, Ann-Cathrin (2020): Cell-derived extracellular matrix as maintaining biomaterial for adipogenic differentiation. - In: Current Directions in Biomedical Engineering 6 (3). - S. 1-4. - DOI: https://doi.org/10.1515/cdbme-2020-3106 | BibTeX | RIS DOIURN |
| Keller, Silke; Liedek, Anke; Shendi, Dalia; Bach, Monika; Tovar, Günter; Kluger, Petra; Southan, Alexander (2020): Eclectic characterisation of chemically modified cell-derived matrices obtained by metabolic glycoengineering and re-assessment of commonly used methods. - In: RSC Advances 10 (58). - S. 35273-35286. - DOI: https://doi.org/10.1039/D0RA06819E | BibTeX | RIS DOIURN |
| Schmidt, Freia; Nowakowski, Sophia; Kluger, Petra (2020): Improvement of a three-layered in vitro skin model for topical application of irritating substances. - In: Frontiers in Bioengineering and Biotechnology 8 (Artikelnummer: 388) - S. 1-11. - DOI: https://doi.org/10.3389/fbioe.2020.00388 | BibTeX | RIS DOIURN |
| Kleinhans, Claudia; Schmohl, Lena; Barz, Jakob; Kluger, Petra (2020): Low-pressure plasma activation enables enhanced adipose-derived stem cell adhesion. - In: Journal of biomedical materials research : Part B, Applied biomaterials 108 (4). - S. 1527-1535. - DOI: https://doi.org/10.1002/jbm.b.34500 | BibTeX | RIS DOI |
2019 | |
| Volz, Ann-Cathrin; Hack, Larissa; Kluger, Petra (2019): A cellulose-based material for vascularized adipose tissue engineering. - In: Journal of biomedical materials research. - Part B, Applied biomaterials 107 (5). - S. 1431-1439. - DOI: https://doi.org/10.1002/jbm.b.34235 | BibTeX | RIS DOI |
| Huber, Birgit; Hoch, Eva; Calderon, Iván; Borchers, Kirsten; Kluger, Petra (2019): A versatile perfusion bioreactor and endothelializable photo cross-linked tubes of gelatin methacryloyl as promising tools in tissue engineering. - In: Biomedical engineering = Biomedizinische Technik 64 (4). - S. 397-406. - DOI: https://doi.org/10.1515/bmt-2018-0015 | BibTeX | RIS DOI |
| Volz, Ann-Cathrin; Omengo, Birgit; Gehrke, Sandra; Kluger, Petra (2019): Comparing the use of differentiated adipose-derived stem cells and mature adipocytes to model adipose tissue in vitro. - In: Differentiation : the journal of the International Society of Differentiation 110 (November - December 2019). - S. 19-28. - DOI: https://doi.org/10.1016/j.diff.2019.09.002 | BibTeX | RIS DOI |
| Nellinger, Svenja; Keller, Silke; Southan, Alexander; Wittmann, Valentin; Volz, Ann-Cathrin; Kluger, Petra (2019): Generation of an azide-modified extracellular matrix by adipose-derived stem cells using metabolic glycoengineering. - In: Current directions in biomedical engineering 5 (1). - S. 393-396. - DOI: https://doi.org/10.1515/cdbme-2019-0099 | BibTeX | RIS DOIURN |
| Novosel, Esther; Borchers, Kirsten; Kluger, Petra; Mantalaris, Athanasios; Matheis, Georg; Pistolesi, Massimo; Schneider, Jörg; Wenz, Annika (2019): New approaches to respiratory assist: bioengineering an ambulatory, miniaturized bioartificial lung. - In: ASAIO Journal 65 (5). - S. 422-429. - DOI: https://doi.org/10.1097/MAT.0000000000000841 | BibTeX | RIS DOI |
2018 | |
| Shkarina, Svetlana; Shkarin, Roman; Weinhardt, Venera; Melnik, Elizaveta; Vacun, Gabriele; Kluger, Petra; Loza, Kateryna; Epple, Matthias (2018): 3D biodegradable scaffolds of polycaprolactone with silicate-containing hydroxyapatite microparticles for bone tissue engineering: high-resolution tomography and in vitro study. - In: Scientific reports 8 (Aufsatz 8907). - S. 1-13. - DOI: https://doi.org/10.1038/s41598-018-27097-7 | BibTeX | RIS DOIURN |
| Volz, Ann-Cathrin; Hack, Larissa; Atzinger, Franziska; Kluger, Petra (2018): Completely defined co-culture of adipogenic differentiated ASCs and microvascular endothelial cells. - In: ALTEX : Alternatives to animal experimentation 35 (4). - S. 464-476. - DOI: https://doi.org/10.14573/altex.1802191 | BibTeX | RIS DOIURN |
| Volz, Ann-Cathrin; Kluger, Petra (2018): Completely serum-free and chemically defined adipocyte development and maintenance. - In: Cytotherapy 20 (4). - S. 576-588. - DOI: https://doi.org/10.1016/j.jcyt.2018.01.004 | BibTeX | RIS DOI |
| Wenz, Annika; Tjoeng, Iva; Schneider, Isabelle; Kluger, Petra; Borchers, Kirsten (2018): Improved vasculogenesis and bone matrix formation through coculture of endothelial cells and stem cells in tissue‐specific methacryloyl gelatin‐based hydrogels. - In: Biotechnology & bioengineering 115 (10). - S. 2643-2653. - DOI: https://doi.org/10.1002/bit.26792 | BibTeX | RIS DOI |
| Schmid, Franziska; Kleinhans, Claudia; Schmid, Freia; Kluger, Petra (2018): Osteoclast formation within a Human co-culture system on bone material as an in vitro model for bone remodeling processes. - In: Journal of functional morphology and kinesiology : JFMK 3 (1). - S. 1-16. - DOI: https://doi.org/10.3390/jfmk3010017 | BibTeX | RIS DOIURN |
2017 | |
| Wenz, Annika; Borchers, Kirsten; Tovar, Günter; Kluger, Petra (2017): Bone matrix production in hydroxyapatite-modified hydrogels suitable for bone bioprinting. - In: Biofabrication 9 (4). - S. 1-14. - DOI: https://doi.org/10.1088/1758-5090/aa91ec | BibTeX | RIS DOI |
| Volz, Ann-Cathrin; Huber, Birgit; Schwandt, Alina Maria; Kluger, Petra (2017): EGF and hydrocortisone as critical factors for the co-culture of adipogenic differentiated ASCs and endothelial cells. - In: Differentiation : the journal of the International Society of Differentiation 95 (May - June 2017). - S. 21-30. - DOI: https://doi.org/10.1016/j.diff.2017.01.002 | BibTeX | RIS DOI |
| Ruff, Sybil Mara; Keller, Silke; Wieland, Daniel; Wittmann, Valentin; Tovar, Günter; Bach, Monika; Kluger, Petra (2017): clickECM : development of a cell-derived extracellular matrix with azide functionalities. - In: Acta biomaterialia (52)- S. 159-170. - DOI: https://doi.org/10.1016/j.actbio.2016.12.022 | BibTeX | RIS DOI |
2016 | |
| Volz, Ann-Cathrin; Huber, Birgit; Kluger, Petra (2016): Adipose-derived stem cell differentiation as a basic tool for vascularized adipose tissue engineering. - In: Differentiation : the journal of the International Society of Differentiation 92 (1-2). - S. 52-64. - DOI: https://doi.org/10.1016/j.diff.2016.02.003 | BibTeX | RIS DOI |
| Huber, Birgit; Engelhardt, Sascha; Meyer, Wolfdietrich; Krüger, Hartmut; Wenz, Annika; Schönhaar, Veronika; Tovar, Günter; Kluger, Petra; Borchers, Kirsten (2016): Blood-vessel mimicking structures by stereolithographic fabrication of small porous tubes using cytocompatible polyacrylate elastomers, biofunctionalization and endothelialization. - In: Journal of functional biomaterials 7 (2). - S. 1-18. - DOI: https://doi.org/10.3390/jfb7020011 | BibTeX | RIS DOIURN |
| Wenz, Annika; Janke, Katharina; Hoch, Eva; Tovar, Günter; Borchers, Kirsten; Kluger, Petra (2016): Hydroxyapatite-modified gelatin bioinks for bone bioprinting. - In: Bionanomaterials : journal of functional materials, biomechanics, and tissue engineering 17 (3-4). - S. 179-184. - DOI: https://doi.org/10.1515/bnm-2015-0018 | BibTeX | RIS DOI |
| Huber, Birgit; Czaja, Alina Maria; Kluger, Petra (2016): Influence of epidermal growth factor (EGF) and hydrocortisone on the co-culture of mature adipocytes and endothelial cells for vascularized adipose tissue engineering. - In: Cell biology international 40 (5). - S. 569-578. - DOI: https://doi.org/10.1002/cbin.10595 | BibTeX | RIS DOI |
| Huber, Birgit; Link, Antonia; Linke, Kirstin; Gehrke, Sandra; Winnefeld, Marc; Kluger, Petra (2016): Integration of mature adipocytes to build up a functional three-layered full-skin equivalent. - In: Tissue engineering / Part C. Methods 22 (8). - S. 756-764. - DOI: https://doi.org/10.1089/ten.tec.2016.0141 | BibTeX | RIS DOIURN |
| Huber, Birgit; Borchers, Kirsten; Tovar, Günter; Kluger, Petra (2016): Methacrylated gelatin and mature adipocytes are promising components for adipose tissue engineering. - In: Journal of biomaterials applications 30 (6). - S. 699-710. - DOI: https://doi.org/10.1177/0885328215587450 | BibTeX | RIS DOI |
2015 | |
| Kleinhans, Claudia; Mohan, Ramkumar; Vacun, Gabriele; Schwarz, Thomas; Haller, Barbara; Sun, Yang; Kahlig, Alexander; Kluger, Petra; Finne-Wistrand, Anna; Walles, Heike; Hansmann, Jan (2015): A perfusion bioreactor system efficiently generates cell-loaded bone substitute materials for addressing critical size bone defects. - In: Biotechnology journal 10 (11). - S. 1727-1738. - DOI: https://doi.org/10.1002/biot.201400813 | BibTeX | RIS DOI |
| Kleinhans, Claudia; Schmid, Freia; Schmid, Franziska; Kluger, Petra (2015): Comparison of osteoclastogenesis and resorption activity of human osteoclasts on tissue culture polystyrene and on natural extracellular bone matrix in 2D and 3D. - In: Journal of biotechnology 205 - S. 101-110. - DOI: https://doi.org/10.1016/j.jbiotec.2014.11.039 | BibTeX | RIS DOIURN |
| Huber, Birgit; Kluger, Petra (2015): Decelerating mature adipocyte dedifferentiation by media composition. - In: Tissue Engineering / Part C : Methods 21 (12). - S. 1237-1245. - DOI: https://doi.org/10.1089/ten.tec.2015.0166 | BibTeX | RIS DOI |
| Huber, Birgit; Volz, Ann-Cathrin; Kluger, Petra (2015): How do culture media influence in vitro perivascular cell behavior?. - In: Cell biology international 39 (12). - S. 1395-1407. - DOI: https://doi.org/10.1002/cbin.10515 | BibTeX | RIS DOI |
| Thude, Sibylle; Kluger, Petra; Schenke-Layland, Katja (2015): In vitro-Hauttestsysteme zur Untersuchung lichtassoziierter Hautschädigung. - In: Biospektrum 21 (2). - S. 172-174. - DOI: https://doi.org/10.1007/s12268-015-0557-z | BibTeX | RIS DOI |
| Surmeneva, Maria; Kleinhans, Claudia; Vacun, Gabriele; Kluger, Petra; Schönhaar, Veronika; Müller, Michaela; Hein, Sebastian Boris; Wittmar, Alexandra; Ulbricht, Mathias; Prymak, Oleg; Oehr, Christian; Surmenev, Oleg (2015): Nano-hydroxyapatite-coated metal-ceramic composite ofiron-tricalcium Phosphate : improving the surface wettability,adhesion and proliferation of mesenchymal stem cells in vitro. - In: Colloids and surfaces B : biointerfaces (135)- S. 386-393. - DOI: https://doi.org/10.1016/j.colsurfb.2015.07.057 | BibTeX | RIS DOI |
| Kleinhans, Claudia; Vacun, Gabriele; Surmenev, Roman; Surmeneva, Maria; Kluger, Petra (2015): Testing the in vitro performance of hydroxyapatite coated magnesium (AZ91D) and titanium concerning cell adhesion and osteogenic differentiation. - In: BioNanoMaterials 16 (1). - S. 41-50. - DOI: https://doi.org/10.1515/bnm-2015-0002 | BibTeX | RIS DOIURN |
| Huber, Birgit; Volz, Ann-Cathrin; Kluger, Petra (2015): Understanding the effects of mature adipocytes and endothelial cells on fatty acid metabolism and vascular tone in physiological fatty tissue for vascularized adipose tissue engineering. - In: Cell & tissue research 362 (2). - S. 269-279. - DOI: https://doi.org/10.1007/s00441-015-2274-9 | BibTeX | RIS DOI |
